Why Is High Fructose Corn Syrup "Evil"?

My Bigger Half and I avoid high fructose corn syrup (HFCS) as much as possible. That's a challenging position to take though because it's ubiquitous! Further, I even reduced my consumption of agave syrup because it has higher fructose content than HFCS. But I've gotten to wondering what's so bad about fructose, especially HFCS. Mr. Skeptic asked me why is HFCS evil, pushing me into more research.

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